JPH0161119B2 - - Google Patents

Info

Publication number
JPH0161119B2
JPH0161119B2 JP56128643A JP12864381A JPH0161119B2 JP H0161119 B2 JPH0161119 B2 JP H0161119B2 JP 56128643 A JP56128643 A JP 56128643A JP 12864381 A JP12864381 A JP 12864381A JP H0161119 B2 JPH0161119 B2 JP H0161119B2
Authority
JP
Japan
Prior art keywords
ethyl
desmethyl
general formula
vinblastine
hydroxyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP56128643A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5772993A (en
Inventor
Dankusui Rayosu
Kebee Teiboa
Fuekete Gyorujii
Detsutsuerii Esutaa
Geeretsugu Sandaaa
Asu Chiiboa
Tsuantai Saba
Sabo Rayosu
Hontei Katarin
Ekuharuto Sandoa
Hini Iban
Keruperuufuroniusu Sandoa
R Suzanna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RIHITAA GEDEON BEGIESUZECHI GIARU AARU TEII
Original Assignee
RIHITAA GEDEON BEGIESUZECHI GIARU AARU TEII
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RIHITAA GEDEON BEGIESUZECHI GIARU AARU TEII filed Critical RIHITAA GEDEON BEGIESUZECHI GIARU AARU TEII
Publication of JPS5772993A publication Critical patent/JPS5772993A/ja
Publication of JPH0161119B2 publication Critical patent/JPH0161119B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP56128643A 1980-10-22 1981-08-17 Cell propagation controlling compounds, manufacture and medicinal composition containing same Granted JPS5772993A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU802563A HU181746B (en) 1980-10-22 1980-10-22 Process for preparing vinblastine and leurosidine derivatives

Publications (2)

Publication Number Publication Date
JPS5772993A JPS5772993A (en) 1982-05-07
JPH0161119B2 true JPH0161119B2 (en]) 1989-12-27

Family

ID=10960009

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56128643A Granted JPS5772993A (en) 1980-10-22 1981-08-17 Cell propagation controlling compounds, manufacture and medicinal composition containing same

Country Status (16)

Country Link
US (2) US4410459A (en])
JP (1) JPS5772993A (en])
AT (1) AT376679B (en])
BE (1) BE889990A (en])
CA (1) CA1182450A (en])
CH (1) CH648321A5 (en])
DE (1) DE3132475A1 (en])
ES (1) ES505311A0 (en])
FR (1) FR2492385B1 (en])
GB (1) GB2086884B (en])
HU (1) HU181746B (en])
IL (1) IL63594A0 (en])
IT (1) IT1138155B (en])
NL (1) NL8103843A (en])
SE (1) SE442117B (en])
SU (1) SU1138033A3 (en])

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU198074B (en) * 1985-06-12 1989-07-28 Richter Gedeon Vegyeszet Process for producing new bis-indole derivatives and pharmaceutical compositions comprising these compounds
HU193318B (en) * 1985-06-12 1987-09-28 Richter Gedeon Vegyeszet Process for producing new bis- indol derivatives
JPH0747233B2 (ja) * 1987-09-14 1995-05-24 古河電気工業株式会社 半田析出用組成物および半田析出方法
US5095109A (en) * 1989-06-08 1992-03-10 University Of Vermont Novel alkaloids
US5938163A (en) * 1997-10-20 1999-08-17 Eastman Kodak Company Articulating touchscreen interface
US20130178618A1 (en) 2012-01-10 2013-07-11 William Allen Boulanger Novel pharmaceutical intermediates and methods for preparing the same
US12116372B1 (en) 2023-12-14 2024-10-15 William Allen Boulanger Process for preparing methyl 3-bromo-2-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)propanoate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4075214A (en) * 1976-05-17 1978-02-21 Eli Lilly And Company Preparation of leurosidine and novel leurosidine 4'-ethers and esters
US4143041A (en) * 1977-01-19 1979-03-06 Eli Lilly And Company 4'-Deoxyvincristine and related compounds
HU178706B (en) * 1979-04-23 1982-06-28 Richter Gedeon Vegyeszet Process for preparing bis-indole alkaloids and acid addition salts thereof
JPS56128642A (en) * 1980-03-15 1981-10-08 Kubota Ltd Production of frozen mold

Also Published As

Publication number Publication date
BE889990A (fr) 1982-02-17
SE442117B (sv) 1985-12-02
IT1138155B (it) 1986-09-17
AT376679B (de) 1984-12-27
FR2492385A1 (fr) 1982-04-23
SU1138033A3 (ru) 1985-01-30
NL8103843A (nl) 1982-05-17
IT8123541A0 (it) 1981-08-17
ES8300778A1 (es) 1982-12-01
US4410459A (en) 1983-10-18
ATA358781A (de) 1984-05-15
FR2492385B1 (fr) 1985-08-02
GB2086884B (en) 1984-07-25
DE3132475C2 (en]) 1991-04-11
IL63594A0 (en) 1981-11-30
HU181746B (en) 1983-11-28
CA1182450A (en) 1985-02-12
DE3132475A1 (de) 1982-06-24
SE8104878L (sv) 1982-04-23
GB2086884A (en) 1982-05-19
US4490378A (en) 1984-12-25
JPS5772993A (en) 1982-05-07
ES505311A0 (es) 1982-12-01
CH648321A5 (de) 1985-03-15

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